Congratulations Dr. Jim Xiang - Top Collaborative Innovation Development Grant Winner
Dr. Jim Xiang was presented the Saskatchewan Health Research Foundation 2017 Top Collaborative Innovation Development Grant Award.
New Publication from Lukong Lab in Oncotarget
FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition
New Publication from Vizeacoumar Lab in Mol Syst BIol
"An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer"
New Publication from Anderson Lab in Sci Rep
"Identification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinase"
New review article published by Lukong Lab in Breast Cancer Res Treat
"Breast cancer in Africa: prevalence, treatment options, herbal medicines, and socioeconomic determinants"
New Publication from Wu, Lukong and Vizeacoumar Labs in Biochem J
"Biochemical characterization of INTS3 and C9ORF80, two subunits of hNABP1/2 heterotrimeric complex in nucleic acid binding"
New Publication from Vizeacoumar Lab in Sci Rep
"The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment"
New Publication from Lukong Lab in Breast Cancer Res Treat
"Breast cancer in Africa: prevalence, treatment options, herbal medicines, and socioeconomic determinants"
Congratulations to Jeremy Marshall - new M.Sc. in Biochemistry
Jeremy Marshall (Anderson lab) passed his MSc defence on October 31, 2017. His thesis is titled: "Structural analysis of the p85 BH domain in complex with binding partners and impact of mutations".
Dr. Jim Xiang Featured in SHRF's "Research for Health" Magazine
The research program of Dr. Xiang was featured in the October-2017 Issue 4 of "Research for Health", a magazine produced by the Saskatchewan Health Research Foundation.
CoMRAD Grant to Dr. Franco Vizeacoumar
Congratulations to Dr. Franco Vizeacoumar, awarded one year a College of Medicine CoMRAD grant for the project: "Overcoming therapeutic drug resistance in human breast cancer".
CoMRAD Grant to Dr. Yuliang Wu
Congratulations to Dr. Yuliang Wu, awarded one year a College of Medicine CoMRAD grant for the project: "KH Domain: Its Role in Helicases and as a Potential Target for Breast Cancer".
CoMRAD Grant to Dr. Erique Lukong
Congratulations to Dr. Erique Lukong, awarded one year a College of Medicine CoMRAD grant for the project: "Role of BRK in tamoxifen-resistant breast cancers".
Dr. Franco Vizeacoumar was awarded a Cancer Research Society Grant
Dr. Franco Vizeacoumar (and co-Applicant Dr. Andrew Freywald) were awarded a 2-year grant from the Cancer Research Society. Title: ‘Polokinase and drug resistance in pancreatic cancer`.
Congratulations Chelsea Cunningham on receiving the Lisa Rendall Breast Cancer Graduate Student Scholarship
Congratulations to Chelsea Cunningham (Vizeacoumar Lab), the recipient of a Lisa Rendall Breast Cancer Graduate Student Scholarship, a two-year award. Chelsea's project is titled: “Exploiting the synthetic dosage lethal interactions of polo-like kinase 1 for breast cancer therapeutics”.
New Publication from Wu and Lukong Labs in J Biol Chem
"The DEAD-box Protein DDX43 (HAGE) Is a Dual RNA-DNA Helicase and Has a K-homology Domain Required for Full Nucleic Acid Unwinding Activity"
Congratulations Raghu Goel, poster winner at the 2017 PSFaM conference
Raghu Goel (Graduate student in the Lukong lab) won a poster prize at the Protein Structure, Function and Malfunction conference held in Saskatoon on June 15-16, 2017. The title of his poster is "Phosphoproteomics analysis identified novel candidate substrates of the non-receptor tyrosine kinase SRMS". Congratulations!
Congratulations Jeremy Marshall, poster winner at the 2017 PSFaM conference
Jeremy Marshall (Graduate student in the Anderson lab) won the Louis Delbaere prize for the best poster with experiments performed at the Canadian Light Source at the Protein Structure, Function and Malfunction conference held in Saskatoon on June 15-16, 2017. The title of his poster is "X-Ray Crystallographic Analysis of the p85 BH Domain". Congratulations!
New Publication from Xiang Lab in Immunotargets
"CD8+ memory T-cell inflation renders compromised CD4+ T-cell-dependent CD8+ T-cell immunity via naïve T-cell anergy"
Congratulations Poster Winners at the fourth Saskatchewan Cancer Research Conference
The fourth Saskatchewan Cancer Research Conference was held June 14, 2017 in Saskatoon, with 108 registered participants from a wide range of disciplines in attendance. This conference recognizes and promotes the excellent cancer research within the province and provides valuable learning and networking opportunities for the participants.
New Publication from Anderson Lab in Breast Cancer Research
"Molecular characterization of breast cancer cell lines through multiple omic approaches"
Dr. Jim Xiang awarded a CIHR Project Grant
Dr. Jim Xiang was awarded a 4-year Project grant from the CIHR for a project called: “Distinct regulation of T cell fate and memory via differentially IL-2- and IL-7-activated mTORC1-KIF13A-M6PR axis and AMPK-FOXO-Eomes pathway”.
Dr. Kalpana Bhanumathy awarded a College of Medicine Post-Doctoral Fellowship
Dr. Kalpana Bhanumathy (Vizeacoumar lab) was awarded a College of Medicine Post-Doctoral Fellowship for one year. The title of her project is "Identification of therapeutically relevant targets for prostate cancer."
New Publication from Xiang Lab in Cell Discov
"mTORC1 regulates mannose-6-phosphate receptor transport and T-cell vulnerability to regulatory T cells by controlling kinesin KIF13A"
New Publication from Vizeacoumar Lab in Sci Rep
"Enhancing the throughput and multiplexing capabilities of next generation sequencing for efficient implementation of pooled shRNA and CRISPR screens"
Dr. Franco Vizeacoumar was awarded a CoMBRIDGE Grant
Dr. Franco Vizeacoumar was awarded a bridge grant from the College of Medicine for a project called: “Targeting chromosomal instability by synthetic dosage lethality”.
Dr. Deborah Anderson was awarded a CoMBRIDGE Grant
Dr. Deborah Anderson was awarded a bridge grant from the College of Medicine for a project called: “New therapies for luminal A and triple negative breast cancer”.
Research Excellence Award from the College of Medicine for Dr. Jim Xiang
Dr. Jim Xiang received a Research Excellence Award from the College of Medicine to support his research program. Congratulations!
Dr. Yuliang Wu awarded a SHRF Collaborative Innovation Development Grant
Dr. Yuliang Wu was awarded a 1-year grant from the Saskatchewan Health Research Foundation, together with co-investigators: Drs. DeCoteau, Xiang, Cygler. Title: ‘Targeting HAGE (DDX43) helicase in acute myeloid leukemia’.
Dr. Jim Xiang awarded a SHRF Collaborative Innovation Development Grant
Dr. Jim Xiang was awarded a 1-year grant from the Saskatchewan Health Research Foundation, together with co-investigators: Drs. Moser, Zhang, Chibbar.
New Publication from Xiang Lab in Biochem Biophys Res Commun
"CD40 agonist converting CTL exhaustion via the activation of the mTORC1 pathway enhances PD-1 antagonist action in rescuing exhausted CTLs in chronic infection"
Translational Team awarded a Saskatchewan Cancer Agency Grant
Dr. Sunil Yadav, and co-applicants, Drs. Andrew Freywald, Franco Vizeacoumar, Deborah Anderson, Henrike Rees, and Louise Quenneville, were awarded a 2-year operating grant from the SCA for a project called: “Identifying EphB6-deficient breast cancer tumors for clinical trials”.
Dr. Shari Smith awarded a Saskatchewan Cancer Agency Postdoctoral Fellowship
Congratulations to Dr. Shari Smith (Anderson lab), the recipient of an SCA Post-Doctoral Fellowship award. The title of her project is “Targeting cancer progression genes upregulated in CREB3L1-deficient breast cancer cells”.
Dr. Keith Bonham awarded a Saskatchewan Cancer Agency Grant
Dr. Keith Bonham, and co-applicant, Dr Franco Vizeacoumar, were awarded a 2-year operating grant from the SCA for a project called: “Identifying targets for combination therapy with Entinostat in triple negative breast cancer”.
Dr. Arun Sudarsan awarded a Saskatchewan Cancer Agency Postdoctoral Fellowship
Congratulations to Dr. Arun Sudarsan (Vizeacoumar lab), the recipient of an SCA Post-Doctoral Fellowship award. The title of his project is “Identifying biomarkers and developing molecular probes for radioimmunotherapy of breast cancer”.
New Publication from Lukong Lab in BBA Clin
"Understanding breast cancer - The long and winding road"
New Publication from Xiang Lab in J Leukoc Biol
"Enhanced suppression of polyclonal CD8+25+ regulatory T cells via exosomal arming of antigen-specific peptide/MHC complexes"
New Publication from Lukong and Bonham Labs in Oncotarget
"Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation"